We offer a variety of production grades to suit your needs.
Each project is tailored to help our clients fulfill their research objectives.
Contact our team to learn more.
Research
High-quality
GMP
(Coming Soon)
Construct new plasmid designs or modify existing plasmids using cutting-edge recombinant DNA techniques.
Plasmid production to 50 milligram scale for research and pre-clinical applications using scalable, GMP-compatible, tech-transferable processes.
Rapid plasmid preps at mini, midi, maxi, mega, and giga scale with turnaround times as short as 3 days and prices as low as $100 per sample.
Comprehensive array of analytical testing services for plasmid DNA quality control.
We provide NGS services for amplicons, plasmids, and microbial genomes with prices as low as $60 per sample.
Denovo synthesis of complex plasmid designs, including large plasmids, poly-A tails, and ITRs.
Transformation of plasmid production strain and preparation of Research Cell Bank.
Scale up cultivation of producing cell line in animal-free process in flasks or bioreactors.
Cell lysis, clarification, chromatographic purification processes, formulation, and vialing.
Complete QC analysis of manufactured material (see available methods below).
Plasmid material shipped to client on dry ice along with Certificate of Analysis.
Denovo synthesis of complex plasmid designs, including large plasmids, poly-A tails, and ITRs.
Transformation of plasmid production strain and preparation of Research Cell Bank.
Scale up cultivation of producing cell line in animal-free process in flasks or bioreactors.
Cell lysis, clarification, chromatographic purification processes, formulation, and vialing.
Complete QC analysis of manufactured material (see available methods below).
Plasmid material shipped to client on dry ice along with Certificate of Analysis.
We offer a variety of production grades to suit your needs.
Each project is tailored to help our clients fulfill their research objectives.
Contact our team to learn more.
(Coming Soon)
Research | High-quality | GMP | |
---|---|---|---|
PROJECT MANAGEMENT | |||
White-glove service with best-in-class project management capabilities | x | x | x |
PLASMID CONSTRUCTION | |||
Scale up of existing plasmid constructs | x | x | x |
DNA synthesis & cloning services for new plasmid construction | x | x | x |
UPSTREAM PROCESS | |||
Production of research cell bank | x | x | x |
Production of master cell bank | x | ||
Animal-free media formulations | x | x | x |
Shake flask production (multiple scales) | x | x | x |
Production in bioreactors (multiple scales) | x | x | |
DOWNSTREAM PROCESS | |||
"Established downstream processes producing quality, transfection-grade material" | x | x | x |
Endotoxin removal | x | x | x |
"Scalable, industry standard downstream process" | x | x | |
Animal-free downstream process | x | x | |
ANALYTICS | |||
Analytical testing services | x | x | x |
Certificate of Analysis | x | x | x |
QC Product release testing | x | x | |
DOCUMENTATION AND QUALITY ASSURANCE | |||
Master Batch Record | x | x | |
Full traceability | x | ||
Production in GMP-certified suite | x | ||
Physical project segregation in dedicated suite | x | ||
Production under QA oversight | x |
QC Analysis | Methodology |
---|---|
Concentration | UV absorption |
Purity | A260/A280 Ratio |
Appearance | Visual inspection |
Plasmid topology | Agarose gel densitometry |
Restriction Digest | Digestion + agarose gel |
Plasmid sequence | NGS |
Residual host DNA | Agarose gel |
Residual RNA | Agarose gel |
Residual protein | BCA assay |
Endotoxin contamination | LAL assay |