Novel Biotechnology
What We Do
Plasmid Engineering, revolutionized
Our Mission
Novel Biotechnology (Biologics) is a technology company with a mission to develop high throughput bacterial platforms in the biotechnology domain. We have selected the plasmid DNA and gene therapy space as our first vertical.
Our Challenge
Plasmid DNA (pDNA) signifies a critical starting point for many genetic engineering tasks.
Continued progress in the gene therapy and DNA/RNA based therapeutic space has led to bottlenecks and growing demands for reliable pDNA material suitable for all applications.
Our Solution
We are developing a high throughput platform that is safer, scalable, adaptable to different plasmid backbones, yields higher quality plasmids, and is many times more productive than E.coli.
Antibiotic free
Process pDNA without relying on antibiotics.
Scalable high throughput
2-17 times more productive than E.Coli based technology.
Plasmid Power
Capable of handling large and complex plasmid constructs.
Fast Cycle Times
Cycle times can be reduced from months to weeks.
Straight-forward Implementation
No major changes to your current manufacturing infrastructure required.
Bacterial Based
Platform is entirely bacterial based, meaning no regulatory hurdles.
Custom Plasmid DNA Manufacturing
- Vector and gene construct design
- Gene library synthesis
- Cloning & bacterial transformation
- Small scale plasmid propagation and purification
Recombinant Protein Manufacturing
- Expression Vector Construct design and synthesis
- Producer cell propagation
- Scale up process development & technology transfer
Custom RNA Manufacturing
- Non-replicating and replicating mRNA
- Construct design & synthesis
- Cell-free IVT & Capping DoE optimization
Nucleic Acids & Protein Analysis
- DNA & RNA sequencing
- Capillary Electrophoresis
- Agarose and denaturing Agarose Gel electrophoresis
- PCR based assays
- SDS-PAGE
- Colorimetric and Fluorometric based assay